| | Course Objectives:
This course is the first course in a two-semester sequence in biochemistry. The students are expected to:
• Demonstrate a good awareness and understanding of biochemical principles
• Understand the main concepts regarding the chemical and physical properties of biomolecules (proteins, carbohydrates and lipids)
• Know the major functions of the biomolecules in a biological system.
• Understand the main concepts of bioenergetics and oxidative phosphorylation. Learning Outcomes:
Knowledge and Understanding:
• Classify biomolecules as belonging to the lipid, carbohydrate, nucleic acid or protein class
• Know the general structures of biomolecules and representative examples for each class
Intellectual skills (cognitive and analytical):
• Correlate the structure of biomolecules to their chemical and physical properties, and influence on biological function.
• Predict the direction of a reaction according to the given bioenergetic data.
| Second Year | | | Course Objectives:
At the end of this Biochemistry laboratory, the students are expected to:
• Learn basic lab techniques that are applied in any routine biochemistry lab.
• Use the knowledge gained in the theoretical classes and how to apply it to understand the basic concepts of detecting biomolecules in vitro.
• Be able to determine some major biomolecules like carbohydrate, lipids, proteins and nucleotides.
Learning Outcomes:
Knowledge and Understanding:
• Know the general laboratory safety and basic techniques.
• Learn how to use basic instruments in any biochemistry lab like Spectrophotometer.
• Learn how to determine some biomolecules like carbohydrates, lipids, and proteins.
Intellectual skills (cognitive and analytical):
• Assess detection techniques of biomolecules.
• Interpret the different methods used in detecting biomolecules and there metabolic pathways.
| Second Year | | | Course Objectives:
This course is the second course in a two-semester sequence in biochemistry. The students are expected to:
• Use the knowledge gained in Biochemistry I to understand the basic concepts of metabolism
• Understand the metabolic pathways of the major biomolecules; carbohydrate, lipids, proteins and nucleotides.
• Understand the main issues regarding the storage and expression of genetic information
Learning Outcomes:
A. Knowledge and Understanding of:
• Mechanisms and examples of signal transduction.
• Major pathways of metabolism.
• Principles of molecular biology including the gene structure, transcription and translation
B. Intellectual skills (cognitive and analytical):
• Integrate metabolic pathways, and analyze the complete integrated metabolic map.
• Interpret metabolic abnormalities and relate them to possible causes and mechanisms.
• Relate the biochemical events at the cellular level to the physiological processes occurring in the whole animal.
• Follow up the flow of genetic information; DNA→RNA→Protein
| Second Year | | | Course Objectives:
At the end of this course, the student is expected to be able to:
• Understand what happens to the body’s chemistry when affected by diseases.
• Know how specimens are collected and processed.
• Relate the changes in water and electrolytes balance, hydrogen ion homoeostasis and blood gases, the kidney function tests, the liver function tests, the carbohydrate metabolism, the plasma proteins, lipids and lipoproteins, to diseases.
Learning Outcomes:
A. Knowledge and understanding of:
• Samples collection and processing.
• Molecular basis of diseases.
• Effects of abnormalities in structure and function of macromolecules.
• Laboratory tests used in the diagnosis of diseases.
B. Intellectual skills (cognitive and analytical):
• Explain molecular basis of diseases.
• Relate the signs and symptoms to the olecular basis of diseases.
| Fourth Year | | | Course Objectives:
• Mathematical background for modeling of the concentration time relationships for the different routes of administration.
• Designing dosing regimens by relating plasma concentration of drugs to their pharmacological and toxicological action,
• Individualization of therapy for patients.
• Designing therapeutic drug monitoring plans for drugs with narrow therapeutic index or high toxicity.
Learning Outcomes:
A) Knowledge and understanding
• Understanding mathematics of the time course of Absorption, Distribution, Metabolism, and Excretion (ADME) of drugs in the body.
• Individualization of therapy and therapeutic drug monitoring for each patient.
B) Intellectual skills (cognitive and analytical)
• Utilization of mathematics of the time course of Absorption, Distribution, Metabolism, and Excretion (ADME) of drugs in the body for dosage optimization.
• Developing dosing regimens for the individualization of therapy for the patient
| Fourth Year |
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