Published Research

Research Title

Authors

Journal

Volume & Page Numbers

Publisher

Year

Thiophene ring-opening reactions. Direct access to the synthesis of 1,3,4-thiadiazoline-(condenced) pyridone hybrids

Mohammed M. Abadleh a, Ahmad H. Abdullah b, Firas F. Awwadi b, Mustafa M. El-Abadelah

Tetrahedron

Elsavier

2021

Synthesis and Cytotoxicity of Thieno[2,3-b]Pyridine Derivatives Toward Sensitive and Multidrug-Resistant Leukemia Cells

Salah A. Al-Trawneh,1,* Amer H. Tarawneh,2 Anastassiya V. Gadetskaya,3 Ean-Jeong Seo,4 Mohammad R. Al-Ta’ani,1 Samir A. Al-Taweel1 and Mustafa M. El-Abadelah5

Acta Chim. Slov. 2021,

68, 458–465

slovenian chemical society

2021

Fused thia-heterocycles via isothiocyanates. Part II. A convenient synthesis of some new thieno [2, 3-b] thiopyran-4-one derivatives

Lana Z El-Agha, Mustafa M El-Abadelah, Marwan R Kamal, Salim S Sabri, Randa M Al-As’ad, Wolfgang Voelter

Zeitschrift für Naturforschung B

73, 109-113

Zeitschrift für Naturforschung B

2018

A study on the reaction of 3-alkyl (aryl) imidazo [1, 5-a] pyridines with ninhydrin

Mervat S Sammor, Mustafa M El-Abadelah, Ahmad Q Hussein, Firas F Awwadi, Salim S Sabri, Wolfgang Voelter

Zeitschrift für Naturforschung B

73, 6, 413-421

De Gruyter

2018

One-Pot Synthesis of Model 1H,1'H-5,5'-Bi(1,2,4-Triazoles)

Mohammed AbadlehMohammed AbadlehMustafa El-abadelahMustafa El-abadelahMonther ZreidMonther Zreid

• Heterocycles 96(6)

96(6), 1080–1087

The Japan institute of heterocyclic chemistry

2018

Fused thia-heterocycles via isothiocyanates. Part I. Facile synthesis of some new 1-benzothiopyran- 4-one derivatives

Lina M. Barhoumi, Mustafa M. El-Abadelah*, Salim S. Sabri and Wolfgang Voelter

Z. Naturforsch.

72(5)b: 369–375

DE GRUYTER

2017

Heterocycles[h]-fused to 4-Oxoquinoline-3-carboxylic acid. Part XI[1]: Synthesis and Antibacterial Activity of 4-Fluoro-6-oxoimidazo[4,5-h]quinoline-7-carboxylic Acids

Jalal A. Zahra, Raed A. Al- Qawasmeh, Mustafa M. El-Abadelah, Mohammed M. Abadleh, Franca Zani, Matteo Incerti, Paola Vicini

Z.Naturforsch

71b, 37-44.

2016

Synthesis and Biological Activity of Some New N1-(4-oxoquinolin-6-yl) amidrazones.

Salma A. Musameh, Salim S. Sabri, Mustafa M. El-Abadelah, Jalal A. Zahra, Mohammed M. Abadleh, Wolfgang Voelter.

Lett. Org. Chem

12, 120-126.

2016

Synthesis and properties of some N-(2,3-dihydrophthalazin-5-yl)amidrazones incorporating piperazines and related congeners

Banan Rawashdeh , M.M.El-Abadelah

Asian Journal Of Chemistry

29 ( 605 - 608 )

Asian Journal Of Chemistry

2016

Synthesis and bioassay of novel substituted pyrano[2,3-f]cinnoline-2-ones

Abla S. Al-zagameem, Mustafa M. El-Abadelah, Malek A. Zihlif, Randa G. Naffa, Musa L. Al-Smadi, and Mohammad S. Mubarak,

Journal of Heterocyclic Chemitry

In Press

2015

A facile synthesis of novel pyridone-annelated spirooxindolepyrrolidines via 1,3-dipolar cycloaddition

Randa M. Al-As’ad , Mustafa M. El-Abadelah, Salim S. Sabri , Jalal A. Zahra, Firas F. Awwadi , Wolfgang Voelter.

Monatsh Chem

146, 621-629.

2015

The Anticancer Activity of the Substituted Pyridone-Annelated Isoindigo (5'-Cl) Invol¬ves G0/G1 Cell Cycle Arrest and Inactivati¬on of CDKs in the Promyelocytic Leukemia Cell Line HL-60.

Ayman M. Saleh, Ahmad Aljada, Mustafa M. El-Abadelah, Mutasem O. Taha, ,Salim. S. Sabri, Jalal.A. Zahra, Mohammad Azhar Aziz.

Cellular Physiology and Biochemistry

35, 1943-1957.

2015

The Pyridone-Annelated Isoindigo (5‘-Cl) Induces Apoptosis, Dysregulation of Mitochondria and Formation of ROS in Leukemic HL-60 Cells.

Ayman M. Saleh, Ahmad Aljada, Mustafa M. El-Abadelah, Salim S. Sabri, Jalal A. Zahra, Amre Nasr, Mohammad A. Aziz.

Cellular Physiology and Biochemistry

35, 1958-1974.

2015

Antiproliferative activity of the isoindigo 5'-Br in HL-60 cells is mediated by apoptosis, dysregulation of mitochondrial functions and arresting cell cycle at G0/G1 phase

Ayman M. Saleha, Mustafa M. El-Abadelah, Mohammad Azhar Aziz, Mutasem O. Tahad, Amre Nasra, Syed A.A. Rizvif.

Cancer Letters

361, 251-261.

2015

Synthesis and characterization of some new flouroquinolone-barbiturate hybrid systems

Kamal Sweidan, Mustafa El-Abadelah, Salim F. Haddad, Wolfgang Voelter.

Z.Naturforsch,

70b, 513-517.

2015

Design, synthesis and antibacterial activity studies of new thiadiazoloquinolone compounds

Raed A. Al-Qawasmeh, Mohammed M. Abadleh, Jalal A. Zahra, Mustafa M. El-Abadelah, Rabab Albashiti, Franca Zani, Matteo Incerti, and Paola Vicini,

Journal of Enzyme Inhibition And Medicinal Chemistry

29, 777-785.

2014

Synthesis and antitumor activity of some new N1-(flavon-6-yl)amidrazone derivatives

Almeqdad Y. Habashneha, Mustafa M. El-Abadelaha, Malek A. Zihlif

Archiv der Pharmazie

347, 415-422

2014

A Facile One-Pot Synthesis of Model Diethyl 6,6'-Dioxotetrahydro-5,5'-bi(1,2,4-triazine)-5,5'-dicarboxylates

Mustafa M. El-Abadelah, Hanan H. Mohammed, Mohammed M.Abadleh, Salim S. Sabri, and Firas F. Awwadi,

Heterocycles

89,1211-1220.

2014

Synthesis and Antitumor Activity of Some N2-(Thien-3-yl)amidrazones

Mohammed M. Abadleh, Mustafa M. El-Abadelah, Salim S. Sabri, Hanan H. Mohammed, Malek A. Zihlif , and Wolfgang Voelter,

Z. Naturforsch

69b , 811-816.

2014

Synthesis and Antibacterial Evaluation of Model Fluoroquinolone-Benzylidene Barbiturate Hybrids

Kamal Sweidan, Walid Abu Rayyan, Musa Abu Zarga, Mustafa M. El-Abadelah and Hani A. Y. Mohammad

Lett. Org. Chem

11, 422-425

2014

A new efficient route to 7-aryl-6-fluoro-8-nitroquinolones as potent antibacterial agents

Salah A. Al-Trawneh, Mustafa M. El-Abadelah, Mohammad M. Al-Abadleh, Franca Zani , Matteo Incerti, Paola Vicini

Eur. J. Med. Chem

56, 364-367

2014

, Synthesis and biological activity of some new N1-(6-fluoro-4-oxoquinolin-8-yl)amidrazones

Mohammed M. Abadleh, Mustafa M. El-Abadelah, Salim S. Sabri, Qasem M. A. Abdallah, Abdelrahman Nasr, and Mohamed F. El-Badawy,

Lett.Org.Chem

11,664-670.

2014

Synthesis and Biological Evaluation of New Pyridone-Annelated Isoindigos as Anti-Proliferative Agents

Ayman M. Saleh, Randa M. Al-As’ad, Mustafa M. El-Abadelah, Salim S. Sabri, Jalal A. Zahra, Ahmed S. Alaskar and Ahmad Aljada,

Molecules,

19, 13076-13092.

2014

Synthesis and Antibacterial Activity of Some Novel 4-Oxopyrido[2,3-a]phenothiazines

Hadeel T. Al-Sinjilawi, Mustafa M. El-Abadelah, Mohammad S. Mubarak, Amal MS. Al-Aboudi, Mohammed M. Abadleh, Adel M. Mahasneh, Asaad K.M.A Ahmad,

Archiv der Pharmazie Chem.. Life Sci.

347, 1-12.

2014

Synthesis of 6-Ethyl-1,2,9-trioxopyrrolo[3.2-f]quinoline-8-carboxylic Acid.

Randa M. Al-As’ad, Mustafa M. El-Abadelah, Salim S. Sabri, Jalal A. Zahra, and Wolfgang Voelter,

Z. Naturforsch.

68b, 706-700.

2013

Heterocycles [f]-Fused onto Quinolones. Synthesis of Novel Dioxo-Nethylpyrano[2,3-f]- and [3,2-f]quinoline-10-carboxylic Acids.

Almeqdad Y. Habashneha, Mustafa M. El-Abadelaha, Mohammad S. Mubaraka, and Wolfgang Voelter,

Z. Naturforsch.

68b, 1049 – 1055.

2013

Synthesis, and antitumor activity of some N1-(flavon-7-yl) amidrazones and related congeners.

Marwa N. Abu Aishah, Mohammad S. Mustafa, Mustafa M. El-Abadelah, Said Ismail, Malek A. Zihlif, Randa Naffa, Mohammad S. Mubarak

Eur. J. Med. Chem.

submitted

2012

Synthesis of Some 1-(Flavon-7-yl)-4,5-dihydro-1,2,4-triazin-6(1H)-ones and Related Congeners.

Marwa N. Abu-Aisheh, Mohammad S. Mustafa, Mohammad S. Mubarak, Mustafa M. El-Abadelah, and Wolfgang Voelter

Lett. Org. Chem

9, 465-473.

2012

Heterocycles [c]-fused onto Indoloquinoxaline. Synthesis of Novel pyrano[2',3':4,5]indolo[2,3-b]quinoxaline-2-ones.

Almeqdad Y. Habashneh, Mustafa M. El-Abadelah, Mohammed M. Abadleh, and Wolfgang Voelter,

Z. Naturforsch

67b, 725-730.

2012

Synthesis and biological evaluation of tetracyclic thienopyridones as antibacterial and antitumor agents

Salah A. Al-Trawneh, Mustafa M. El-Abadelah, Jalal A. Zahra, Samir A. Al-taweel, Franca Zani, Matteo Incerti, Andrea Cavazzoni, Paola Vicini

Bioorg. med. Chem.

19, 2541-2548.

2011

One-Pot Synthesis of 2,5-Bis(3-indolyl)-3,4-dinitrothiophene, 3-(2-Chloro-3,4-dinitrothien-2-yl)-indole and Related Congeners.

Ismail I. Fasfous, Mustafa M. El-Abadelah, Salim S. Sabri

Lett. Org. Chem.

8, 712-716.

2011

Synthesis, and antitumor activity of some N1-(coumarin-7-yl) amidrazones and related congeners.

Mohammad S. Mustafa, Mustafa M. El-Abadelah, Malek A. Zihlif, Randa Naffa, Mohammad S. Mubarak

Molecules

16, 4305-4317.

2011

Concise Synthesis and Displacement Reactions of Model 3-(Alkylthio)-6-chloro- and 2,6-dichlorothieno[2,3-e]-1,4,2-dithiazine 1,1-Dioxides.

Rajab Abu-El-Halawa, Mohanad Masad, Yaser Bathich, Mahmoud Al-Refai, Mohammad M. Ibrahim, Mustafa M. El-Abadelah, and Wolfgang Voelter

Z. Naturforsch

66b, 715-720.

2011

Synthesis of Some Cyclic Methylene 1,3-Diaza Barbiturates Derivatives.

Kamal Sweidan, Jörn Engelmann, Rajendra Joshi, Mohammad S. Mubarak, Mustafa M. El-Abadelah

Lett. Org. Chem.

8, 603-605.

2011

Heterocycles [h]-Fused to 4-Oxoquinoline-3-carboxylic Acid. Part IX: Synthesis of 2,6-Dioxotetrahydro-1H-pyrrolo[3,2-h]quinoline-7-carboxylic Acid.

Jalal A. Zahra, Hala I. Al-Jaber, Mustafa M. El-Abadelah, Mohammad M. Al-Abadleh

Heterocycles

83, 2165-2175.

2011

Synthesis and antibacterial properties of new N4-acetylated hexahydro-2,7-dioxopyrido[2,3-f]quinoxaline-8-carboxylic acids.

Yusuf M. Al-Hiari, Ashok K. Shakya, Muhammed H. Alzweiri, Tariq M Al-Qirim, Ghassan Shattat, Mustafa M. El-Abadelah

J. Enz. Inhib. Med. Chem.

26, 649-656.

2011

Synthesis of Some 1,3-Dimethyl-6-substituted-1H- pyrazolo[3,4-b]pyrazin-5(4H)-ones.

Kayed A. Abu Safieh, Feda'a S. Al-Masri, Mikdad T. Ayoub, Mustafa M. El-Abadelah, and Wolfgang Voelter

Z. Naturforsch.

66b, 1136–1140.

2011

Synthesis and properties of some N-(coumarin-7-yl)-4,5-dihydro-1,2,4-triazin-6(1H)-ones.

Mohammad S. Mustafa, Mustafa M. El-Abadelah, Mohammad. S. Mubarak, Ihekwereme Chibueze, Di Shao and Remigius. U. Agu

Int. J. Chem.

3, 89-103.

2011

Synthesis and Biological Activity of Some 3-(4-(Substituted)-piperazin-1-yl)cinnolines.

Eman D. Awad, Mustafa M. El-Abadelah, Suzan Matar, Malek A. Zihlif, Randa G. Naffa, Ehab Q. Al-Momani and Mohammad S. Mubarak

Molecules

17, 227-239.

2011

Thienopyridone Antibacterials. Part IV. Synthesis of Some N(7)-Heteroaryl-4-oxothieno[2,3-b]pyridine-5-carboxylic Acids and Esters.

Nuha I. Sweidan, Musa Z. Nazer, Mustafa M. El-Abadelah, and Wolfgang Voelter

Lett. Org. Chem.

7, 79-84.

2010

Synthesis and biological evaluation of tetracyclic fluoroquinolones as antibacterial and anticancer agents

Salah A. Al-Trawneh, Jalal A. Zahra, Marwan R. Kamal, Mustafa M. El-Abadelah, Franca Zani, Matteo Incerti, Andrea Cavazzoni, Roberta R. Alfieric, Pier G. Petronini, Paola Vicini

Bioorg. med. Chem.

18, 5873–5884.

2010

New synthesis and antiparasitic activity of model 5-Aryl-1-methyl-4-nitroimidazoles.

Saadeh, Haythem A.; Mosleh, Ibrahim M.; El-Abadelah, Mustafa M.

Molecules

14, 2758-2767.

2009

Heterocycles [h]-fused to 4-oxoquinoline-3-carboxylic acid. Part VII: synthesis of some 6-oxoimidazo[4,5-h]quinoline-7-carboxylic acids and esters.

Al-Dweik, Maram R.; Zahra, Jalal A.; Khanfar, Monther A.; El-Abadelah, Mustafa M; Zeller, Klaus-Peter; Voelter, Wolfgang

Monatshefte fuer Chemie

140, 221-228.

2009

Convenient Synthesis of 1-Alkyl-3-Nitro-4-quinolones

Raed A. Al-Qawasmeh, Jalal A. Zahra, Monther A. Khanfar, Yusuf M. AL-Hiari, Mustafa M. El-Abadelah and Wolfgang Voelter.

Lett. Org. Chem

6, 511-514.

2009

Thienopyridone antibacterials. Part V. Synthesis of some N (7)-azacyclo-hexyl-4-oxotheino[2,3-b]pyridine-5-carboxylic acids and related congeners.

Hala I. Al-Jaber , Mustafa M. El-Abadelah, Salim S. Sabri, Taleb H. Al-Tel, and Wolfgang Voelter.

Z. Naturforsch.

64b,1625-1632.

2009

Synthesis and antibacterial activity of 9-cyclopropyl-4-fluoro-6-oxo-6,9-dihydro-[1,2,5]thiadiazolo[3,4-h]quinoline-7-carboxylic acid and its ethyl ester.

Raed A. Al-Qawasmeh, Jalal A. Zahra, Franca Zani, Paola Vicini, Roland Boese, Mustafa M. El-Abadelah.

ARCHIVOC

(xii),322-336.

2009

Preparation of indolo[2,3-b]-, indeno[1,2-b]-, and indeno[2,1-b]pyrido[2,3-f]quinoxaline-3-carboxylates as antiviral, antibacterial, and antitumor agents.

Boese, Roland; El Abadelah, Mustafa M.; Zahra, Jalal A

Eur. Pat. Appl

EP 2128160 A1, 20091202, 29pp.

2009

[a]Fused Heterocyclic Pyrido[2,3-f]Quinoxaline-2-Carboxylic Acid Derivatives and their Pyrido[3,2-g] Analogs. A Process for their Preparation and their Potential Uses as Anticancer and Antibacterial Agents

Al-Hiari, Yusuf M.; Qaisi, Ali M.; Zahra, Jalal A.; Hassuneh, Mona R.; El-Abadelah, Mustafa M

Jordan Patent (priority date 12/4/2005), filed as a British Patent and will appear in February 2008 – UK Patent (following amendments recommended by the Patent office).

2008

Heterocycles [h]Fused onto 4-Oxoquinoline-3-carboxylic Acid, V. Formal Synthesis and Antibacterial Activity of Some New 7-oxo-7,10-dihydropyrido[2,3-f]quinoxaline-8-carboxylic Acids and Esters.

E. S. Abu–Sheaib, J. A. Zahra, M. M. El-Abadelah.

Z. Naturforsch.

63b, 555-563.

2008

Heterocycles [h]-Fused onto 4-Oxoquinoline-3-carboxylic Acid, Part VI [1]. Synthesis and X-Ray Structure of Model Indolo[2,3-b]- and [3,2-b]pyrido[2,3-f]quinoxaline-3-carboxylic Esters.

E. S. Abu–Sheaib, J. A. Zahra and M. M. El-Abadelah, R. Boese

Monatshefte fuer Chemie

139, 1061-1066.

2008

. Metal- Assisted Oxidative Cyclization of Arylamidrazones II [1]. Novel Synthesis of 1,4-Diaryl[1,2,4]triazino[6,5-h]quinolines.

M. A. Khanfar, B. A. Abu Thaher, J. A. Zahra, M. M. El-Abadelah, W. Voelter.

Z. Naturforsch.

63b, 1107-1111.

2008

Facile synthesis of model indazolo[2,1-c][1,3,4]benzotriazepine-5,13-diones.

Zahra, Jalal A.; El-Abadelah, Mustafa M; Abu Thaher, Bassam A.; Laufer, Stefan; Boese, Roland.

Heterocycles

75, 2989-3004.

2008

Heterocycles [h]-fused onto 4-oxoquinoline-3-carboxylic acid, part VIII [1]. Convenient synthesis and antimicrobial properties of substituted hexahydro[1,4]diazepino[2,3-h]quinoline-9-carboxylic acid and its tetrahydroquino[7,8-b]benzodiazepine analog.

Al-Hiari, Yusuf M.; Abu-Dahab, Rana; El-Abadelah, Mustafa M.

Molecules

13, 2880-2893.

2008

Facile synthesis of 2-(substituted amino)-4H-thieno[3,2-e]-1,3-thiazin-4-ones

Abu-El-Halawa, Rajab; Sarabi, Alaa; El-Abadelah, Mustafa M

Monatshefte fuer Chemie

139, 1251-1255.

2008

Synthesis of novel N-substituted 6-chlorothieno[2,3-e]-1,4,2-dithiazin-3-amine 1,1-dioxides.

Abu-El-Halawa, Rajab; Al-Refai, Mahmoud H.; El-Abadelah, Mustafa M; Tabba, Hani D.

Heterocycles

75, 1749-1755.

2008

Synthesis of 5-Substituted 1,3-Dimethylpyrazolo[4,3-e][1,2,4]triazines.

Abu Safieh, Kayed A.; Abu Mahthieh, Ahmad M.; El-Abadelah, Mustafa M; Ayoub, Mikdad T.; Voelter, Wolfgang,

Monatshefte fuer Chemie

138, 157-160.

2007

Heterocycles [h]fused on 4-oxoquinoline-3-carboxylic acid. Part II. A facile synthesis of some 2,7-dioxo[1,4]thiazino[2,3-h]quinoline-8-carboxylic acids.

Al-Huniti, Mohammed H.; Zahra, Jalal A.; El-Abadelah, Mustafa M,

Heterocycles

71, 411-418.

2007

Facile synthesis of some novel pyrido[3',2':4,5] thieno[2,3-b][1,4]thiazine-8-carboxylic acids.

Al-Huniti, Mohammed H.; El-Abadelah, Mustafa M; Zahra, Jalal A.; Sabri, Salim S.; Ingendoh, Arnd,

Molecules

12, 497-503.

2007

Pictet-Spengler synthesis of some new indolo[2,3-c]quinolines.

Dabaien, Saida A.; El- Abadelah, Mustafa M.; Haddad, Salim F.; Duddeck, Helmut,

Heterocycles

71, 835-846.

2007

Synthesis of Some Ethyl 3-(Aryldiazenyl)-7-oxo-dihydropyrido[2,3-f]quinoxaline-8-carboxylates.

J. A. Zahra, M. A. Khanfar, M. M. El-Abadelah, B. A. Abu Thaher, N. S. EL-Abadla, W. Voelter,

Z. Naturforsch

62b, 1045-1051.

2007

Heterocycles [h]Fused onto 4-Oxoquinoline-3-Carboxylic acid, Part IV. Convenient Synthesis of Substituted Hexahydro[1,4]thiazepino[2,3-h]quinoline-9-carboxylic Acid and its Tetra-hydroquino[7,8-b]benzo- thiazepine Homolog.

M. H. Al-Huniti, M. M. El-Abadelah, J. A. Zahra, S. S. Sabri, A. Ingendoh,

Molecules

12, 1558-1568.

2007

Heterocycles [h]-Fused onto 4-Oxoquinoline-3-carboxylic Acid, III.1 Facile Synthesis and Antitumor Activity of Model Heterocycles[a]-Fused onto Pyrido[2,3-f]quinoxaline-3-carboxylic Acids.

M. Y. Abu Shuheil, M. R. Hassuneh, Y. M. Al-Hiari, A. M. Qaisi, M. M. El-Abadelah,

Heterocycles

71, 2155-2172.

2007

Synthesis of 8-Substituted 12-Methyl-12H-imidazo[4',5':2,3][1,4]diazepino[6,7,1-jk]carbazoles.

Kayed A. Abu Safieh, Fouad H. Darras, Mikdad T. Ayoub, Mustafa M. El-Abadelah, Salim S. Sabri, Wolfgang Voelter,

Heterocycles

71, 2681-2688.

2007

Pictet - Spengler Synthesis of some Thiophene [c]-fused β-carbolines.

Abu Safieh, Kayed A.; Moosa, Basem A.; El-Abadelah, Mustafa M; Sabri, Salim S.; Voelter, Wolfgang,

Monatshefte fuer Chemie

138, 157-160.

2007

Synthesis and antibacterial Potency of 4-Methyl-2,7-dioxo-1,2,3,4,7,10-hexahydropyrido[2,3-f]quinoxaline-8-carboxylic acid, selected [a]Fused-Heterocycles and Acyclic Precursors.

Y. M. Al-Hiari, A. M. Qaisi, M. Y. Abu Shuheil, M. M. El-Abadelah, W. Voelter

Z. Naturforsch

62b, 1453-1458.

2007

Synthesis and Antibacterial Activity of Some Substituted 3-(Aryl)- and 3-(Heteroaryl)indoles.

Al-Hiari, Yusuf M.; Qaisi, Ali M.; El-Abadelah, Mustafa M; Voelter, Wolfgang.

Monatshefte fuer Chemie

137, 243-248.

2006

Synthesis and properties of some new 1,4-dihydrothieno[3,2-e][1,2,4]triazepin-5-ones.

Sabri, Salim S.; El-Abadla, Naser S.; El-Abadelah, Mustafa M; Voelter, Wolfgang.

Z. Naturforsch

61b, 65-68.

2006

Heterocycles [h]Fused Onto 4-Oxoquinolines. Part I. Synthesis of 6-Oxo-6,9-dihydro[1,2,5]oxadiazolo[3,4-h]-quinoline-7-carboxylic acid N-oxide.

Al-Hiari, Yusuf M.; Khanfar, Monther A.; Qaisi, Ali M.; Abu Shuheil, Mohammad Y.; El-Abadelah, Mustafa M; Boese, Roland.

Heterocycles

68, 1163-1172.

2006

Metal-Assisted Oxidative Cyclization of Arylamidrazones I. Synthesis of 3-Acetyl-1,4-dihydro-1-phenyl-1,2,4-benzotriazine.

Al-Noaimi, Mousa Z. ; Abdel-Jalil, Raid J.; El-Abadelah, Mustafa M; Haddad, Salim F. ; Baqi, Younis N. H.; Voelter, Wolfgang.

Monatshefte fuer Chemie

137, 745-750.

2006

Synthesis and Properties of Some Dihydrotetrazolo[5,1-c][1,2,4]triazines.

Zahra, Jalal A.; El-Abadelah, Mustafa M; Abu Thaher, Bassam A.; El-Abadla, Naser S.; Boese, Roland

Heterocycles

68, 1559-1605.

2006

Facile Synthesis of Dihydro-1,2,4-benzotriazepin-5-ones.

Hindawi, Nisreen I.; Zahra, Jalal A.; El-Abadelah, Mustafa M; Abu Thaher, Bassam A.; Zeller, Klaus-Peter,

Monatshefte fuer Chemie

137, 1349-1355.

2006

Preparation of quinolones and pyridoquinoxalinones as antibacterials,

Qaisi, A. M. A.; Al-Hiari, Y. M. A.; Zahra, J. A. Y.; El-Abadelah, M. M. M.,

Eur Pat. Appl.

45pp. EP 1721898 A1 20061115.

2006

On the Synthesis of Some 2-(Arylhydrazono)-3-oxothieno[2,3-b]pyridines by Reaction of Nitrilimines with 2-Mercaptonicotinic Acid.

Zahra, Jalal A.; Abu Thaher, Bassam; El-Abadelah, Mustafa M; Otto, Hans-Hartwig.

Monatshefte fuer Chemie

136, 567-570.

2005

An Efficient One-Pot Synthesis of Pyrazolopyrimidines, Intermediates for Potential Phosphodiesterase Inhibitors.

Abdel-Jalil, Raid J.; Khanfar, Monther; Abu-Safieh, Kayed; Al-Gharabli, Samer; El-Abadelah, Mustafa; Voelter, Wolfgang.

Monatshefte fuer Chemie

136, 619-624.

2005

3-Mercaptopropionic acid-nitrile imine adducts. An unprecedented cyclization into 1,3,4-thiadiazol-2(3H)-ones and -2(3H)-thiones.

Zahra, Jalal A.; Abu Thaher, Bassam A.; El-Abadelah, Mustafa M; Boese, Roland

Organic & Biomolecular Chemistry

3, 2599-2603.

2005

High throughput synthesis of pyrazolopyrimidines via copper-catalysed cyclization and X-ray study.

Abdel-Jalil, Raid J.; Khanfar, Monther; Al-Gharabli, Samer; El-Abadelah, Mustafa M; Eichele, Klaus; Anwar, Muhammad Usman; Voelter, Wolfgang.

Heterocycles

65, 1821-1827.

2005

On the synthesis of 3-acetyl-1-aryl-1,4,5,6-tetrahydro-1H-1,2,4-triazepin-7-ones by reaction of nitrilimines with 3-aminopropanoic acid.

Abu Thaher, Bassam; Zahra, Jalal A.; El-Abadelah, Mustafa M; Otto, Hans-Hartwig.

Monatshefte fuer Chemie

135, 435-439.

2004

A convenient synthesis of some new 1, 3, 4-Benzothiadiazepin-5-ones.

Zahra, Jalal A.; Abu Thaher, Bassam A.; El-Abadelah, Mustafa M; Boese, Roland.

Heterocycles

63, 1153-1163.

2004

Ring size influence on the cyclocondensation mode of GABA - nitrile imine adducts.

Abu Thaher, Bassam A.; Zahra, Jalal A.; El-Abadelah, Mustafa M; Voelter, Wolfgang.

Z. Naturforsch.

59b, 930-933.

2004

Direct conversion of an ortho-allylphenol into a chlorosulfonyl-3-methyl-1,2-benzoxathiin 2,2-dioxide.

Qaisi, Li M.; El-Abadelah, Mustafa M; Voelter, Wolfgang.

Z. Naturforsch.

59b, 1059-1062.

2004

New synthesis of model dihydroazepine-fused indolo[2,3-c]quinolines.

Al-Khashashneh, Adel M.; El-Abadelah, Mustafa M; Boese, Roland.

Heterocycles

60, 73-87.

2003

An alternative synthesis of 2-(N-arylhydrazono)-1-benzothiophen-3-ones.

Zahra, Jalal A.; Abu Thaher, Bassam A.; El-Abadelah, Mustafa M; Boese, Roland.

Organic & Biomolecular Chemistry

1, 822-825.

2003

Synthesis and dopamine receptor binding of some pyrazolo[3',4': 6,7]azepino[5,4,3-cd]indoles.

Gmeiner, Peter; Hubner, Harald; Safieh, Kayed A. Abu; Fasfous, Ismail I.; El-Abadelah, Mustafa M; Sabri, Salim S.; Voelter, Wolfgang.

Heterocycles

60, 1339-1350.

2003

Investigations on the structure of 4-methyldihydro-1,3,4-benzotriazepin-5-ones. Tautomer reassignment.

Zahra, Jalal A.; El-Abadelah, Mustafa M; Nazer, Musa Z.; Ebraheem, Kais A. K.; Boese, Roland.

Organic & Biomolecular Chemistry

1, 1798-1801.

2003

Pictet-Spengler synthesis of pyrazole-fused ß-carbolines.

Fasfous, Ismail I.; El-Abadelah, Mustafa M; Sabri, Salim S.

Journal of Heterocyclic Chemistry

39, 225-227.

2002

Chiroptical properties of some (S)-N,N'-bis[(1-phenyl-5-alkyl-4,5-dihydro-6-oxo-1,2,4-triazin-3-yl)ethylidene] propane-1,3-diamine nickel(II).

Abushamleh, A. S.; El-Abadelah, Mustafa M ; Voelter, Wolfgang.

Journal of the Chemical Society of Pakistan

24, 31-35.

2002

Synthesis of some thiophene-fused azepino[5,4,3 - cd]indoles.

Moosa, Basem A.; Abu Safieh, Kayed A.; El-Abadelah, Mustafa M.

Heterocycle

57, 1831-1840.

2002

Facile synthesis of model 1,4-dihydro-1H-1,3,4-benzotriazepin-5-ones.

Abu Thaher, Bassam A.; Zahra, Jalal A.; El-Abadelah, Mustafa M.

Journal of Heterocyclic Chemistry

39, 901-904.

2002

Synthesis and properties of isoViagra. A 2-methyl-2H-pyrazolo[4,3-d]pyrimidin-7-one isomer of Viagra.

El-Abadelah, Mustafa M; Sabri, Salim S.; Khanfar, Monther A.; Yasin, Hani A.; Voelter, Wolfgang.

Journal of Heterocyclic Chemistry

39, 1055-1059.

2002

Bischler-Napieralski synthesis of some new pyrazole-fused ß-carbolines.

Abu-Safieh, Kayed A.; El-Abadelah, Mustafa M; Sabri, Salim S.; Voelter, Wolfgang; Moessmer, Acilia M.; Stroebele, Markus.

Z. Naturforsch.

57b, 1327-1332.

2002

Tautomerism and X-ray structure of dihydro-5H-1,3,4-benzotriazepin-5-ones.

Zahra, Jalal A.; Abu Thaher, Bassam A.; El-Abadelah, Mustafa M; Klinga, Martti.

Heterocycles

57, 2365-2371.

2002

Transition metal complexes of derivatized chiral dihydro-1,2,4-triazin-6-ones, part IV. Synthesis and structural characterization of a copper(II) complex of (L)-3-acetyl-5-benzyl-1-phenyl-4,5-dihydro-1,2,4-triazin-6-one oxime.

El-Abadelah, Mustafa M; Abushamleh, Ahmad S.; Moessmer, Caecilia M.; Voelter, Wolfgang.

Z. Naturforsch.

57b, 547-551.

2002

Phosphodiesterase-inhibiting pyrazolopyrimidinone derivatives conjugated to thiophene moieties or benzo [fused] 5-membered heterocycles for treatment of erectile dysfunction and other cardiovascular disorders.

Abdel-Jalil, Raid; Al-Abed, Yousef; El-Abadelah, Mustafa M; Khanfar, Monther; Sabri, Salim S.; Voelter, Wolfgang.

PCT Int. Appl.

37 pp.

2001

Preparation of sildenafil analogs for treatment of erectile dysfunction.

Badwan, Adnan Ali H.; El Abadelah, Mustafa M. M.

U.S. Pat. Appl.,

10 pp.

2001

Synthesis of pyrazole-fused azepino[5,4,3-cd]indoles.

Abu Safieh, Kayed A.; El-Abadelah, Mustafa M; Sabri, Salim S.; Abu Zarga, Musa H.; Voelter, Wolfgang; Moessmer, Cacilia M.

Journal of Heterocyclic Chemistry

38, 623-628.

2001

An expeditious synthesis of optically pure 1,4,5,6-tetrahydro-as-triazines, fused to the carbohydrate skeleton.

Saeed, Muhammad; Abdel-Jalil, Raid J.; Voelter, Wolfgang; El-Abadelah, Mustafa M.

Chemistry Letters

660-661.

2001

Synthesis and vasorelaxant potency of monagra. A chiral 5-(2-methyl-2,3-dihydro-7-benzofuryl)pyrazolopyrimidone analog of Viagra.

Al-Bojuk, Nader R.; El-Abadelah, Mustafa M; Sabri, Salim S.; Michel, Alain; Voelter, Wolfgang; M.-Moessmer, Cacilia; Al-Abed, Yousef.

Heterocycles

55, 1789-1803.

2001

Transition metal complexes of derivatized chiral dihydro-1,2,4-triazin-6-ones. Part I. Nickel(II) complex of (D)-3-acetyl-5-benzyl-1-phenyl-4,5-dihydro-1,2,4-triazin-6-one oxime. An instance of a carbon-carbon coupling reaction.

Abushamleh, Ahmad S.; El-Abadelah, Mustafa M; Moessmer, Cacilia M.

Heterocycles

53, 1155-1165.

2000

Synthesis and structural characterization of palladium(II) complex with (L)-3-acetyl-5-benzyl-1-phenyl-4,5-dihydro-1,2,4-triazin-6-one oxime. Part II.

Abushamleh, Ahmad S.; El-Abadelah, Mustafa M; Moessmer, Cacilia M.

Heterocycles

53(8), 1737-1744.

2000

Synthesis and Properties of Some 2,3-Disubstituted 6-Fluoro-7-(4-methyl-1-piperazinyl)quinoxalines.

Abdel-Jalil, Raid J.; Al-Qawasmeh, Raed A.; Voelter, Wolfgang; Heeg, Peter; El-Abadelah, Mustafa M; Sabri, Salim S.

Journal of Heterocyclic Chemistry

37, 1273-1275.

2000

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Published Research