We are interested on preparation of new heterocyclic compounds containing indole, benzofuran, quinoline and benzothiophene-2-carboxamide derivatives then investigate them as potential anticancer agents.
In addition, synthesis of new organic derivatives of barbituric and meldrum’s acids; which may exhibit antibacterial and antifungal activities.
Characterization of the target products using spectroscopic techniques (NMR, IR), MS, elemental analysis and single crystal X-ray diffraction.
Isolation, Identification and Synthesis of Impurities/degradants in Pharmaceutical Raw Materials and Finished Products.
Semi-Preparative HPLC and Plate chromatography for Isolation Purpose.
LC/MS and 2D-NMR techniques for characterization the target impurities.
Development and validation of HPLC methods for analysis Pharmaceutical Active Ingredients and their related impurities.