Published Research

Research Title

Authors

Journal

Volume & Page Numbers

Publisher

Year

8-Amino-7-(aryl/hetaryl)fluoroquinolones. An emerging set of synthetic antibacterial agents

Ala’a A. Al-Akhras, Jalal A. Zahra*, Mustafa M. El-Abadelah*, Lubna F. Abu-Niaaj and Monther A. Khanfar

Zeitschrift für Naturforschung C,

vol. 78, no. 3-4, 2023, pp. 157-168.

2023

Thiophene ring-opening reactions VI. Attempted cyclization towards [fused]-tricyclic system involving a thiolate anion and suitably located electrophilic carbon

Ahmad H Abdullah, Jalal A Zahra, Salim S Sabri, Firas F Awwadi, Ahmad Q Hussein, Mustafa M El-Abadelah

Zeitschrift für Naturforschung C

78(3–4)c: 133–140

De Gruyter

2023

Thermodynamic control synthesis of spiro[oxindole-3,3′-pyrrolines] via 1,4-dipolar cycloaddition utilizing imidazo[1,5-a]quinoline

Areej M Jaber, Jalal A Zahra, Mustafa M El-Abadelah, Salim S Sabri, Dua’a S Sabbah

Zeitschrift für Naturforschung C

78(3–4)c: 140-148

De Gruyter

2023

Thiophene Ring-opening Reactions III: One- pot Synthesis and Antitumor Activity of 1,3,4- thiadiazoline-benzothiazolo[3,2- b]pyridazine Hybrids

Ahmad H. Abdullah, Jalal A. Zahra1, Salim S. Sabri, Firas F. Awwadi , Mohammed M. Abadleh, Qasem M. Abdallah and Mustafa M. El-Abadelah

Current Organic Synthesis

19, 279-290

Bentham Science

2022

One-pot synthesis of novel 2-oxo (2H)-spiro [benzofuran-3, 3′-pyrrolines] via 1, 4-dipolar cycloaddition reaction

Mohammed M Al-Mahadeen, Jalal A Zahra, Mustafa M El-Abadelah, Areej M Jaber, Monther A Khanfar

Results in Chemistry

4, 100643

Elsevier

2022

New Trends in 1, 4-Dipolar Cycloaddition Reactions. Thermodynamic Control Synthesis of Model 2'-(isoquinolin-1-yl)-spiro [oxindole-3, 3'-pyrrolines]

Areej M Jaber, Jalal A Zahra, Salim S Sabri, Monther A Khanfar, Firas F Awwadi, Mustafa M El-Abadelah

Current Organic Chemistry

26, 542-549

Bentham Science Publishers

2022

Thiophene Ring-Opening Reactions IV. Facile Generation of Novel Ethyl 4-hydroxy-6-thioxonicotinate-1, 3, 4-thiadiazoline Hybrids

Mohammed M Abadleh, Ahmad H Abdullah, Jalal A Zahra, Salim S Sabri, Firas F Awwadi, Mustafa M El-Abadelah

Letters in Organic Chemistry

19, 504-510

Bentham Science Publishers

2022

Thiophene Ring-Opening Reactions V. Expedient Synthesis of 1, 3, 4-Thiadiazoline-Sulfanyl [1, 3] thiazin-4-one Hybrids

Abdullah K Jarrar, Mustafa M El-Abadelah, Salim S Sabri, Jalal A Zahra, Mohammad S Hamdan

Letters in Organic Chemistry

19, 976-982

Bentham Science Publishers

2022

Synthesis and properties of N1-(indan-5-yl)amidrazones incorporating piperazines and related congeners

Daldoom, Eslam S.; Qadri, Malak I.; Zahra, Jalal A.; Sabri, Salim S.; El-Abadelah, Mustafa M.; Khanfar, Monther A.; Bardaweel, Sanaa; Voelter, Wolfgang

Letters in Organic Chemistry

18(1), 41-48

Bentham Science Publishers Ltd.

2021

HPLC/MS-MS identification of oak Quercus aegilops root tannins

Amr, Ayed S.; Ahmad, Mousa N.; Zahra, Jalal A.; Abdullah, Mai A.

journal of Chemistry

Volume 2021, Article ID 8882050, 10 pages

Hindawi

2021

Thiophene ring-opening reactions II. Easy synthesis of 1,3,4-thiadiazoline-sulfanylpyridazine hybrids

Abdullah, Ahmad H.; El-Abadelah, Mustafa M.; Zahra, Jalal A.; Sabri, Salim S.; Awwadi, Firas F.

Monatshefte fuer Chemie

152 (7) Pages853-862

Splinger LINK

2021

Utilization of 1-phenylimidazo[1,5-a]quinoline as partner in 1,4-dipolar cycloaddition reactions

Jaber, Areej M.; Zahra, Jalal A.; El-Abadelah, Mustafa M.; Sabri, Salim S.; Khanfar, Monther A.; Voelter, Wolfgang

eitschrift fuer Naturforschung, B: A Journal of Chemical Sciences

Volume75 Issue3 Pages259-267

Walter de Gruyter GmbH

2020

Synthesis and Properties of N1-(indan-4-yl)amidrazones Incorporating Piperazines and Related Congeners

Eslam S. Daldoom, Salim S. Sabri, Mustafa M. El-Abadelah, Monther A. Khanfar, Ala’a A. Al-Akhras and Jalal A. Zahra*

Jordan Journal of Chemistry

Volume 14, Number 3, September 2019 Pages 121-130

2019

Synthesis and Anticancer Properties of Methyl N1-(thien-4-yl)amidrazone- 3-carboxylates

Almansour, Ali M.; Zahra, Jalal A.; Sabri, Salim S.; El-Abadelah, Mustafa M.; Zihlif, Malik A.; Taha, Mutasem O.

Letters in Drug Design & Discovery

olume15 Issue12 Pages1268-1275

Bentham Science Publishers Ltd.

2018

Heterocycles [h]-fused to 4-oxoquinoline- 3-carboxylic acid. Part XI: Synthesis and antibacterial activity of 4-fluoro-6- oxoimidazo[4,5-h]quinoline-7-carboxylic acids

Jalal A. Zahra*, Raed A. Al-Qawasmeh, Mustafa M. El-Abadelah, Mohammed M. Abadleh, Franca Zani, Matteo Incerti, Paola Vicini and Wolfgang Voelter*

Zeitschrift für Naturforschung B

71(1)b: 37–44

DE GRUYTER

2016

Synthesis and Biological Activity of Some New N1-(4-oxoquinolin-6-yl)amidrazones

Musameh, Salma A.; Sabri, Salim S.; El-Abadelah, Mustafa M.; Zahra, Jalal A.; Abadleh, Mohammed M.; Voelter, Wolfgang

Letters in Organic Chemistry

Volume13 Issue2 Pages120-126

Bentham Science Publishers Ltd.

2016

Synthesis and antibacterial activity of N1-(carbazol-3-yl)amidrazones incorporating piperazines and related congeners

Abdullah, Ahmad H.; Zahra, Jalal A.; El-Abadelah, Mustafa M.; Sabri, Salim S.; Khanfar, Monther A.; Matar, Suzan A.; Voelter, Wolfgang

Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences

Volume71 Issue8 Pages857-867

Walter de Gruyter GmbH

2016

A facile synthesis of novel pyridone-annelated spirooxindolepyrrolidines via 1,3-dipolar cycloaddition

Al-As'ad, Randa M.; El-Abadelah, Mustafa M.; Sabri, Salim S.; Zahra, Jalal A.; Awwadi, Firas F.; Voelter, Wolfgang

Monatshefte fuer Chemie

Springer-Verlag GmbH

2015

The Pyridone-Annelated Isoindigo (5‘-Cl) Induces Apoptosis, Dysregulation of Mitochondria and Formation of ROS in Leukemic HL-60 Cells

Ayman M. Saleha, Ahmad Aljadaa, Mustafa M. El-Abadelah, Salim S. Sabri, Jalal A. Zahra, Amre Nasra, Mohammad A. Azizb

Cellular Physiology and Biochemistry

35:1958-1974

karger

2015

The Anticancer Activity of the Substituted Pyridone-Annelated Isoindigo (5'-Cl) Involves G0/G1 Cell Cycle Arrest and Inactivation of CDKs in the Promyelocytic Leukemia Cell Line HL-60

Ayman M. Saleha, Ahmad Aljadaa, Mustafa M. El-Abadelah, Mutasem O. Taha Salim S. Sabri, Jalal A. Zahra, Mohammad Azhar Aziz

Cellular Physiology and Biochemistry

35:1943-1957

Karger

2015

Synthesis and biological evaluation of new pyridone-annelated isoindigos as anti-proliferative agents

Saleh, Ayman M.; Al-As'ad, Randa M.; El-Abadelah, Mustafa M.; Sabri, Salim S.; Zahra, Jalal A.; Alaskar, Ahmed S.; Aljada, Ahmad

Molecules

19, 13076-13092

MDPI AG

2014

Design, synthesis and antibacterial activity studies of new thiadiazoloquinolone compounds

Al-Qawasmeh, Raed A.; Abadleh, Mohammed M.; Zahra, Jalal A.; El-Abadelah, Mustafa M.; Albashiti, Rabab; Zani, Franca; Incerti, Matteo; Vicini, Paola

Journal of Enzyme Inhibition and Medicinal Chemistry

29, 777-785

Informa Healthcare

2014

Heterocycles [h]-fused onto 4-oxoquinoline-3-carboxylic acid. Part X. Synthesis and X-ray structure of a model 4-oxo[1,4]benzoxazepino[2,3-h]quinoline-3-carboxylic ester

Farrayeh, Batool A.; El-Abadelah, Mustafa M.; Zahra, Jalal A.; Haddad, Salim F.; Voelter, Wolfgang

Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences

68, 187-194

Verlag der Zeitschrift fuer Naturforschung

2013

Synthesis of 6-ethyl-1,2,9-trioxopyrrolo[3,2-f]quinoline-8-carboxylic acid

Al-As'ad, Randa M.; El-abadelah, Mustafa M.; Sabri, Salim S.; Zahra, Jalal A.; Voelter, Wolfgang

Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences Volume68 Issue5/6 Pages700-706

68, 700-706

Verlag der Zeitschrift fuer Naturforschung

2013

Synthesis and biological evaluation of tetracyclic thienopyridones as antibacterial and antitumor agents

Al-Trawneh, Salah A.; El-Abadelah, Mustafa M.; Zahra, Jalal A.; Al-Taweel, Samir A.; Zani, Franca; Incerti, Matteo; Cavazzoni, Andrea; Vicini, Paola

Bioorganic & Medicinal Chemistry

19(8), 2541-2548

Elsevier B.V.

2011

Heterocycles [h]-Fused to 4-Oxoquinoline-3-carboxylic Acid. Part IX. Synthesis of 2,6-Dioxotetrahydro-1H-pyrrolo[3,2-h]quinoline-7-carboxylic Acid

Zahra, Jalal A, Al-Jaber, Hala I., El-Abadelah, Mustafa M., Al-Abadleh, Mohammad M.

Heterocycles

83 (9)

Japan Institute of Heterocyclic Chemistry

2011

Synthesis and biological evaluation of tetracyclic fluoroquinolones as antibacterial and anticancer agents.

Al-Trawneh, Salah A.; Zahra, Jalal A.; Kamal, Marwan R.; El-Abadelah, Mustafa M.; Zani, Franca; Incerti, Matteo; Cavazzoni, Andrea; Alfieri, Roberta R.; Petronini, Pier G.; Vicini, Paola

Bioorganic & Medicinal Chemistry

18(16), 5873-5884

Elsevier B.V.

2010

Synthesis and antibacterial activity of 9-cyclopropyl-4-fluoro-6-oxo-6,9-dihydro-[1,2,5]thiadiazolo[3,4-h]quinoline-7-carboxylic acid and its ethyl ester.

Al-Qawasmeh, Raed A.; Zahra, Jalal A.; Zani, Franca; Vicini, Paola; Boese, Roland; El-Abadelah, Mustafa M

ARKIVOC

(12), 322-336.

Arkat USA Inc.

2009

A convenient synthesis of 1-alkyl-7-chloro-6-fluoro-3-nitro-4-quinolones.

Al-Qawasmeh, Raed A.; Zahra, Jalal A.; Khanfar, Monther A.; Al-Hiari, Yusuf M.; El-Abadelah, Mustafa M.; Voelter, Wolfgang.

Letters in Organic Chemistry

6(6), 511-514.

Bentham Science Publishers Ltd.

2009

Heterocycles [h]-fused to 4-oxoquinoline-3-carboxylic acid. Part VII: synthesis of some 6-oxoimidazo[4,5-h]quinoline-7-carboxylic acids and esters.

Al-Dweik, Maram R.; Zahra, Jalal A.; Khanfar, Monther A.; El-Abadelah, Mustafa M.; Zeller, Klaus-Peter; Voelter, Wolfgang.

Monatshefte fuer Chemie

140(2), 221-228

SpringerWienNewYork

2009

Facile synthesis of model indazolo[2,1-c][1,3,4]benzotriazepine-5,13-diones.

Zahra, Jalal A.; El-Abadelah, Mustafa M.; Thaher, Bassam A.; Abu Laufer, Stefan; Boese, Roland.

Heterocycles

75(12), 2989-3004

Japan Institute of Heterocyclic Chemistry

2008

Metal-assisted oxidative cyclization of arylamidrazones II [1]. Novel synthesis of 1,4-diaryl[1,2,4]triazino[6,5-h]quinolines.

Khanfar, Monther A.; Thaher, Bassam A. Abu.; Zahra, Jalal A.; Al-Qawasmeh, Raed A.; El-Abadelah, Mustafa M.; Voelter, Wolfgang.

Zeitschrift fuer Naturforschung, B: Chemical Sciences

63(9), 1107-1111

Verlag der Zeitschrift fuer Naturforschung

2008

Heterocycles [h]-fused onto 4-oxo-quinoline-3-carboxylic acid. Part VI. Synthesis and X-ray structure of model indolo[3,2-b]- and [2,3-b]pyrido[2,3-f]quinoxaline-3-carboxylic esters.

Abu-Sheaib, Esraa S.; Zahra, Jalal A.; El-Abadelah, Mustafa M.; Boese, Roland.

Monatshefte fuer Chemie

139(9), 1061-1066

Springer Wien

2008

Heterocycles [h]-fused onto 4-oxoquinoline-3-carboxylic acid, V [1]. Synthesis and antibacterial activity of some new 2,3-disubstituted 7-oxo-7,10-dihydropyrido[2,3-f]quinoxaline-8-carboxylic acids and esters.

Abu-Sheaib, Esra'a S.; Zahra, Jalal A.; El-Abadelah, Mustafa M.; Voelter, Wolfgang.

eitschrift fuer Naturforschung, B: Chemical Sciences

63(5), 555-563

Verlag der Zeitschrift fuer Naturforschung

2008

1,4-Dihydroxyquinoxaline-2,3(1H,4H)-dione.

Abu-El-Halawah, Rajab; Ali, Basem Fares; Ibrahim, Mohammad M.; Zahra, Jalal A.

Acta Crystallographica, Section E: Structure Reports Online

E64(3), o571-o572, o571/1-o571/9.

Blackwell Publishing Ltd.

2008

Reaction of nitrilimines with 2-substituted aza-heterocycles. Synthesis of pyrrolo[1,2-a]pyridine and pyrimido[2,1-d]1,2,3,5-tetrazine.

Awadallah, Adel M.; Zahra, Jalal A.

Molecules

13(1), 170-176.

Molecular Diversity Preservation International

2008

Oxidative cyclization of arylidene carboxyhydrazides: synthesis of substituted hydroxydiphenylmethyl-1,3,4-oxadiazoles.

Abu Safieh, Kayed A.; Al-Titi, Ahmad M. S.; Zahra, Jalal A.; Ayoub, Mikdad T.

Jordan Journal of Chemistry

2(3), 211-218.

Yarmouk University

2007

Heterocycles [h]fused onto 4-oxoquinoline-3-carboxylic acid, Part IV. Convenient synthesis of substituted hexahydro[1,4]thiazepino[2,3-h]quinoline-9-carboxylic acid and its tetrahydroquino[7,8-b]benzothiazepine homolog.

Al-Huniti, Mohammed H.; El-Abadelah, Mustafa M.; Zahra, Jalal A.; Sabri, Salim S.; Ingendoh, Arnd.

Molecules

2(8), 1558-1568

Molecular Diversity Preservation International

2007

Synthesis of some ethyl 3-(aryldiazenyl)-7-oxodihydropyrido[2,3-f]quinoxaline-8-carboxylates.

Zahra, Jalal A.; Khanfar, Monther A.; El-Abadelah, Mustafa M.; Abu Thaher, Bassam A.; El-Abadla, Naser S.; Voelter, Wolfgang.

Zeitschrift fuer Naturforschung, B: Chemical Sciences

62(8), 1045-1051.

Verlag der Zeitschrift fuer Naturforschung

2007

Facile synthesis of some novel pyrido[3',2':4,5]thieno[2,3-b][1,4]thiazine-8-carboxylic acids.

Al-Huniti, Mohammed H.; El-Abadelah, Mustafa M.; Zahra, Jalal A.; Sabri, Salim S.; Ingendoh, Arnd.

Molecules

12(3), 497-503

Molecular Diversity Preservation International

2007

Heterocycles [h]fused on 4-oxoquinoline-3-carboxylic acid. Part II. A facile synthesis of some 2,7-dioxo[1,4]thiazino[2,3-h]quinoline-8-carboxylic acids.

Al-Huniti, Mohammed H.; Zahra, Jalal A.; El-Abadelah, Mustafa M.

Heterocycles

71(2), 411-418

Japan Institute of Heterocyclic Chemistry

2007

Facile Synthesis of Dihydro-1,2,4-benzotriazepin-5-ones.

Hindawi, Nisreen I.; Zahra, Jalal A.; El-Abadelah, Mustafa M.; Abu Thaher, Bassam A.; Zeller, Klaus-Peter.

Monatshefte fuer Chemie

37(10), 1349-1355

Springer Wien

2006

Synthesis and properties of some dihydrotetrazolo[5,1-c][1,2,4]triazines.

Zahra, Jalal A.; El-Abadelah, Mustafa M.; Abu Thaher, Bassam A.; El-Abadla, Naser S.; Boese, Roland.

Heterocycles

68(8), 1595-1605

Japan Institute of Heterocyclic Chemistry

2006

3-Mercaptopropionic acid-nitrile imine adducts. An unprecedented cyclization into 1,3,4-thiadiazol-2(3H)-ones and -2(3H)-thiones.

Zahra, Jalal A.; Abu Thaher, Bassam A.; El-Abadelah, Mustafa M.; Boese, Roland.

Organic & Biomolecular Chemistry

3(14), 2599-2603.

Royal Society of Chemistry

2005

On the Synthesis of Some 2-(Arylhydrazono)-3-oxothieno[2,3-b]pyridines by Reaction of Nitrilimines with 2-Mercaptonicotinic Acid.

Zahra, Jalal A.; Thaher, Bassam Abu; El-Abadelah, Mustafa M.; Otto, Hans-Hartwig.

Monatshefte fuer Chemie

36(4), 567-570

Springer Wien

2005

Ring size influence on the cyclocondensation mode of GABA - nitrile imine adducts.

Abu Thaher, Bassam A.; Zahra, Jalal A.; El-Abadelah, Mustafa M.; Voelter, W.

Zeitschrift fuer Naturforschung, B: Chemical Sciences

59(8), 930-933

Verlag der Zeitschrift fuer Naturforschung

2004

A convenient synthesis of some new 1, 3, 4-Benzothiadiazepin-5-ones.

Zahra, Jalal A.; Thaher, Bassam A. Abu; El-Abadelah, Mustafa M.; Boese, Roland.

Heterocycles

63(5), 1153-1163

Japan Institute of Heterocyclic Chemistry

2004

On the synthesis of 3-acetyl-1-aryl-1,4,5,6-tetrahydro-1H-1,2,4-triazepin-7-ones by reaction of nitrilimines with 3-aminopropanoic acid.

Abu Thaher, Bassam; Zahra, Jalal A.; El-Abadelah, Mustafa M.; Otto, Hans-Hartwig.

Monatshefte fuer Chemie

35(4), 435-439.

Springer-Verlag Wien

2004

Investigations on the structure of 4-methyldihydro-1,3,4-benzotriazepin-5-ones. Tautomer reassignment.

Zahra, Jalal A.; El-Abadelah, Mustafa M.; Nazer, Musa Z.; Ebraheem, Kais A. K.; Boese, Roland.

Organic & Biomolecular Chemistry

1(10), 1798-1801

Royal Society of Chemistry

2003

An alternative synthesis of 2-(N-arylhydrazono)-1-benzothiophen-3-ones.

Zahra, Jalal A.; Thaher, Bassam A. Abu; El-Abadelah, Mustafa M.; Boese, Roland.

Organic & Biomolecular Chemistry

1(5), 822-825

Royal Society of Chemistry

2003

Tautomerism and X-ray structure of dihydro-5H-1,3,4-benzotriazepin-5-ones.

zahra, Jalal A.; Thaher, Bassam A. Abu; El-Abadelah, Mustafa M.; Klinga, Martti.

Heterocycles

57(12), 2365-2371

Japan Institute of Heterocyclic Chemistry

2002

Facile synthesis of model 1,4-dihydro-1H-1,3,4-benzotriazepin-5-ones.

Thaher, Bassam A. Abu; Zahra, Jalal A.; El-Abadelah, Mustafa M.

Journal of Heterocyclic Chemistry

39(5), 901-904

HeteroCorporation

2002

Synthesis of a building block for phosphonate analogs of moenomycin A12 from D-tartaric acid.

Zahra, Jalal; Hennig, Lothar; Findeisen, Matthias; Giesa, Sabine; Welzel, Peter; Muller, Dietrich; Sheldrick, William S.

Tetrahedron

57(46), 9437-9452

Elsevier Science Ltd

2001

Synthesis of a building block for phosphonate analogs of moenomycin A12 from D-tartaric acid.

Zahra, J.; Hennig, L.; Findeisen, M.; Welzel, P.; Muller, D.; Sheldrick, W. S.

Tetrahedron Letters

42(16), 2969-2972

Elsevier Science Ltd

2001

Chemical constituents of Capsella bursa-pastoris.

l-Khalil, Suleiman; Abu Zarga, Musa; Zeitoun, Nissreen; Al-Eisawi, Dawud; Zahra, Jalal; Sabri, Salim; Atta-Ur-Rahman.

Alexandria Journal of Pharmaceutical Sciences

14(2), 91-94

University of Alexandria, Faculty of Pharmacy

2000

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Published Research