| | | Development and characterization of a novel bovine milk protein composed of bovine serum albumin and bovine insulin: A possible potent diabetogen – This project is intended to develop a novel bovine milk novel protein composed of bovine serum albumin and bovine insulin, characterization of the newly developed bovine milk protein, and studying structural changes which might be occurred to the protein conformation due to protein-protein interaction, which will be characterized by exploiting the effect of the Nuclear magnetic resonance T2 relaxation time on the protein kinetics. The outcomes are expected to provide an integral approach toward better understanding of the pathogenesis of type 1 immune-mediate diabetes mellitus, which could provide further insights into the possible primary prevention of the disease. Principal investigator: Dr. Hayder A. Al-Domi (h.aldomi@ju.edu.jo), participating investigators: Dr. Moh'd Al Zwari, Dr Imad Hamdan, and Dr. Ziad Jaradat. Budget: US$ 35,500.Funding body: Deanship of Academic Research, The University of Jordan, Jordan. | | | | Obesity among young Jordanians: Eating practices and genetic predisposition - This project seeks, as an initial effort, to establish a baseline dietary profile and the physical activity levels for young Jordanian children aged 12-18 years old in Jordan as well as to determine genetic factors that act as an effect modifier for environmental risk factors of obesity. Principal investigator: Dr. Hayder Al-Domi (h.aldomi@ju.edu.jo). Participating investigators: Dr. Ahmad Faqih, Dr. Ziad Jaradat and Dr. Saeid Jaradat. Budget: US$ 21, 000. Funding body: Deanship of Academic Research, The University of Jordan, Jordan. | | | | The effect of vitamin D supplementation on chromium serum levels and insulin resistance among overweight Jordanian women with polycystic ovary syndrome in Irbid, Jordan – The objective of this prospective randomized double blind placebo-controlled clinical trial is to examine the effect of vitamin D supplementation on PCOS, chromium serum level, insulin resistance measured by using hyperinsulinemic glycemic clamp and body weight among women aged(15-49 years and diagnosed with PCOS and vitamin D deficiency in Irbid, Jordan. Principal investigator: Dr. Hayder Al-Domi (h.aldomi@ju.edu.jo). Participating investigators: Dr. Ahmad Faqih, Dr. Ziad Jaradat and Dr. Saeid Jaradat. Budget: US$ 21, 000. Funding body: Deanship of Academic Research, The University of Jordan, Jordan. Principal investigator: Dr. Hayder A. Al-Domi (h.aldomi@ju.edu.jo). Participating investigators: Dr Ashraf Faheem; Faculty of Medicine, Jordan University of Science and Technology (JUST).Nahal Subhi Al-Bayari (PhD candidate, JU). Budget: US$ 30,000.00. Funding body: Deanship of Academic Research, The University of Jordan, Jordan , and Al-Hayat Pharmaceuticals, Jordan. | | | | Determination of certain serum pro-inflammatory biomarkers induced by overweight and its relationship with body weight status assessed by bioelectrical impedance analysis – The purpose of this project is to determine serum levels of pro-inflammatory biomarkers (IL-1β, IL-6, TNF- and CRP) and sex hormone-binding globulin(SHBG) overweight young adults aged 18-30 years old as compared to normal weight participants evaluated by using bioelectrical impedance analysis compared to that evaluated by using classical anthropometric measurements. The findings of this study could provide means to control the progress of obesity-related diseases. Principal investigator: Dr. Hayder Al-Domi (h.aldomi@ju.edu.jo). Calling for participating investigators to take part in the study. |
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