Published Research

Research Title

Authors

Journal

Volume & Page Numbers

Publisher

Year

The Effect of Pomegranate Juice on the Expression of Some Murine UDPGlucuronosyltransferases

Yacoub M. Irshaid*, Ruba Alani, Razan Al-Rawashdeh, Tuqa Al-Ghazawi, Hiba Hijazi, Dana Amara, Amena Hammad, Zaineh M. Shahrure and Mohammad Al Shhab

Drug Metabolism Letters

14 (1): 89-93,2021

Bentham Science Publishers

20201

SLCO1B1 Gene Polymorphisms (rs2306283 and rs4149056) and Statin-Induced

Zaineh M. Shahrure, Yacoub M. Irshaid*, Khader N. Mustafa, Mousa A. Abujbara, Mohammad Al Shhab, Mohammed S. El-Khateeb and Kamel M. Ajlouni.

Current Clinical Pharmacology

16:1-8, 2020

Bentham Science Publishers

2020

The effect of licorice drink on cytochrome P3A6 and P-glycoprotein gene transcription in rabbits

Rawia A. Al-Balawnih, Suheil M. Zmeili, Yacoub M. Irshaid, Malek A. Zihlif

Medicine Science International Medical Journal

6(1):35-40

2017

Methylene tetrahydrofolate reductase genotypes frequencies: association with the toxicity of and response to methotrexate in rheumatoid arthritis patients

Saleh MM, Irshaid YM, Mustafa KN

International Journal of Clinical Pharmacology and Therapeutics

53(2):154-62

2015

Association of rs7041 and rs4588 Polymorphisms of the Vitamin D Binding Protein and the rs10741657 Polymorphism of CYP2R1 with Vitamin D Status Among Jordanian Patients

Lafi Zainab M., Irshaid Yacoub M, El-Khateeb Mohammed, Ajlouni Kamel M., and Hyassat Dana

Genetic Testing and Molecular Biomarkers

19(11): 629-636

2015

The A1166C Polymorphism of the AT1R Gene is Associated with an Early Onset of Hypertension and High Waist Circumference in Jordanian Males Attending The Jordan University Hospital

Dima S Shahin, Yacoub M Irshaid and Akram Abu Saleh

Clinical and Experimental Hypertension

36(5):333-339

2014

Association of MDR1 C3435T and RFC1 G80A polymorphisms with methotrexate toxicity and response in Jordanian rheumatoid arthritis patients

Sima A. Samara, Yacoub M. Irshaid, and Khader N. Mustafa

International Journal of Clinical Pharmacology and Therapeutics

52(9):746-755

2014

Thiopurine S- methytransferase Gene Polymorphism in Jordanian Healthy Volunteers and Patients with Rheumatoid Arthritis

Asma M. Elawi, Yacoub M. Irshaid, Said I. Ismail, and Khader N. Mustafa.

Archives of Medical Research

Accepted, 2013

2013

N-Acetyltransferase-2 Genotypes Among Jordanian Patients With Diabetes Mellitus.

52. Y. M. Irshaid, M. A. Abujbara, K. M. Ajlouni, M. El-Khateeb, and Y. B. Jarrar.

International Journal of Clinical Pharmacology and Therapeutics

51(7):593-599,2013.

2013

Cholesteryl Ester Transfer Protein rs1532624 Gene Polymorphism is Associated with Reduced Response to Statin Therapy

Alaa' Yehya, Yacoub Irshaid and Akram Abu Saleh

Current Molecular Pharmacology

6(3):156-162

2013

The Effect of Pomelo Mix Ethyl Acetate Extract on CYP3A6 and P-glycoprotein Gene Transcripts in Rabbits

Yacoub M. Irshaid, Malek A. Zihlef, Suheil M Zmeili, Eman T. Al-Antary, Mais G. Zmaily, Somya N. Al-Embideen, and Abdallah O. Amireh

Drug Metabolism Letters

7:137-140

2013

N-Acetyltransferase-2 Genotypes Among Patients With Rheumatoid Arthritis Attending Jordan University Hospital.

Muna K. Oqal, Khader N. Mustafa, and Yacoub M. Irshaid.

Genetic Testing and Molecular Biomarkers

16(9):1007-1010

2012

Discrepancies Between Elderly Patient's Self-Reported and Prescribed Medications: A Social Investigation.

Nada A. Yasein, Farihan F. Barghouti, Yacoub M. Irshaid.

Scandinavian Journal of Caring Sciences

doi:10.1111/j.1471-6712.2012.01012.x, 2012.

2012

Elderly patients in Family Practice: Polypharmacy and Inappropriate Prescribing: Jordan

Nada A. Yasein, Farihan Bargouti, Yacoub M. Irshaid.

International Medical Journal

19(4):302-306

2012

Frequency of certain single nucleotide polymorphisms and duplication of CYP2D6 in the Jordanian population.

Malek Zihlif, Amer Imraish, Yacoub M. Irshaid.

Genetic Testing and Molecular Biomarkers

16(10):1201-1205

2012

Prescription pattern of antihypertensive drugs in Family Practice Clinics at Jordan University Hospital.

Essam Al-Drabah, Yacoub Irshaid, Nada Yasein, Suhail Zmeili.

Med Science

doi:10.5455/MedScience2012.01.8047

2012

Use of antihypertensive medications among elderly patients with metabolic syndrome attending family practice clinic

Nada A. Yasein, Yacoub M. Irshaid, Farihan F. Bargouti, Wejdan A. Shroukh, Lana J.Halaseh.

International Medical Journal

Accepted 2012

2012

The Effect of Ethyl Acetate Extract of Pomelo Mix on Systemic Exposure of Verapamil in Rabbits

Suad Aqel, Yacoub Irshaid, Munir Gharaibeh, and Tawfiq Arafat

Drug Metabolim Letters

5(2):92-98.

Bentham Science

2011

Pharmacokinetics of Vancomycin in Neonates Admitted to the Neonatology Unit at Jordan University Hospital

Eman Badran, Abdulqader Shamayleh, and Yacoub Irshaid

International journal of Clinical Pharmacology and Therapeutics

49(4):252-257

Dustri-Verlag

2011

Effect of Mint-drink on Metabolism of Nicotine as Measured by Nicotine to Cotinine Ratio in Urine of Jordanian Smoking Volunteers.

Abdulrahman M Ghazi, Abdulazim S salhab, Tawfiq A Arafat, Yacoub M Irshaid

Nicotine and Tobacco Research

Published online March 31,2011 (doi: 10.1093/ntr/ntr054. 13(8):661-667,2011

2011

Prescription pattern of nonsteroidal anti-inflammatory drugs in a Family Practice Clinic at Jordan University Hospital.

Nada A Yasein, Farihan Barghouti, Fatin T Al Faris, Lana N Hatamleh, Mohammed S Farah, Yacoub M Irshaid

Jordan Medical Journal

45(1):9-17

2011

The Effect of Licorice Drink on the Systemic Exposure of Verapamil in Rabbits.

Ibraheem D. Al-Deeb, Tawfeeq A. Arafat and Yacoub M. Irshaid.

Drug Metabolism Letters

4:173-179

Bentham

2010

N-Acetyltransferase-2 (NAT2) Genotype Frequency Among Jordanian Volunteers.

Yazun B. Jarrar, Said Ismail, and Yacoub M. Irshaid.

International Journal of Clinical Pharmacology and Therapeutics

48:688-694

Dustri-Veralg

2010

Pharmacokinetics of Gentamicin in Hemodialysis Patients: A Comparative Study Between Diabetic and Non-diabetic Patients

Mohammed A. Al-Homrany, Yacoub M. Irshaid, Assem K. El Sherif and Haider A. Omar.

International Urology and Nephrolog, Published online 2008

41:663-669

2009

Pharmacoepidemiological Study of Prescription Pattern of Analgesics, Antipyretics, and Nonsteroidal Antiinflammatory Drugs at a Tertiary Health Care Center.

Mohammed A. Al Homrany and Yacoub M. Irshaid.

Saudi Medical Journal

Vol. 28, No.3

2007

Compliance with the Legal Elements of Prescriptions in Outpatient Clinics of a Teaching Hospital in Southwestern Saudi Arabia. Eastern

Yacoub M. Irshaid, Mohammed Al Homrany, Anwar A. Hamdi, Keneth K. Adjepon-Yamoah and Ahmed A. Mahfouz.

Mediterranean Health Journal

Vol. 11, No.(5/6):

2005

Snake bites and Scorpion stings in Children: an audit of cases admitted to Asir Central Hospital, South-western Saudi Arabia

Mohammed Al-Shehri and Yacoub Irshaid.

Middle East Paediatrics

Vol.10, No.1

2005

An Epidemiological Study of Prescription Pattern for Upper Respiratory Tract Infections in a Tertiary Health Care Center in Southwestern Saudi Arabia

Yacoub M. Irshaid, Mohammed A. Al Homrany, and Anwar Hamdi

Saudi Medical Journal

Vol.26, No.10

2005

Appropriatness of Requests for Therapeutic Drug Monitoring of Antiepileptic Drugs.

Yacoub M. Irshaid, Anwar A. Hamdi and Mohammed Al Homrany.

Clinical Laboratory

Vol. 50, No.(3+4):

2004

A Pharmacoepiemiological Study of Prescription Pattern in Outpatient Clinics of a Teaching Hospital in Southwestern Saudi Arabia.

Yacoub M. Irshaid, Mohammed Al Homrany, Anwar A. Hamdi, Keneth K. Adjepon-Yamoah and Ahmed A. Mahfouz.

Saudi Medical Journal

Vol. 25, No.12

2004

Effect of famotidine and diclofenac on theophylline pharmacokinetics in the rabbit

Sameer Otoom, Kamal A. Hadidi, Yacoub Irshaid, Abdel-Kader Battah, and Hakam F. Hadidi

Asian Journal of Chemistry

16(3):1403-1409

2004

Evaluation of Therapeutic Drug Monitoring of Antiepileptic Drugs

Yacoub M. Irshaid, Anwar A. Hamdi and Mohammed Al Homrany

Int Journal of Clinical Pharmacology and Therapeutics.

Vol. 41, No.3

2003

Comparative pharmacokinetics of two nifedipine products in capsule form following single oral administration in healthy volunteers.

Rawashdeh NM, Battah AH, Irshaid YM, and Al Qato MK

European Journal of Drug metabolism and Pharmacokinetics

Vol. 22, No.3

1997

Metabolic interactions of putative cytochrome P4503A substrates with alternative pathways of dapsone metabolism in human liver microsomes

Yacoub Irshaid, Robert A. Branch and Adedayo Adedoyin

Drug Metabolism and Disposition

Vol. 24, No.2

1996

Comparative pharmacokinetics of two brands of atenolol following a single oral administration.

Y. M. Irshaid, N. M. Rawashdeh, F. F. Awwadi and M. K. Kato.

Int. Journal of Clinical Pharmacology and Therapeutics

Vol. 34, No.10

1996

Dextromethorphan metabolism in Jordanians: Dissociation of dextromethorphan O-demethylation from debrisoquine 4-hydroxylation.

Y. M. Irshaid, H. F. AL-Hadidi, A. Latif, F. Awwadi, M. Al-Zoubi And N. M. Rawashdeh

European Journal of Drug metabolism and Pharmacokinetics

Vol. 21, No.4

1996

The N-oxidation of trimethylamine in a Jordanian population.

H. F. Hadidi, S. Cholerton, S. Atkinson, Y. M. Irshaid, N. M. Rawashdeh and J. R. Idle

British Journal of Clinical Pharmacology

1995

Comparative Pharmacokinetics of 2 brands of cefuroxime following a single intramuscular injection

Y. M. Irshaid, N.M. Rawashdeh, F. Zghoul, I. Jalal and N. M. Najib

Int. Journal of Clinical Pharmacology and Therapeutics

Vol. 33, No.5

1995

S-Mephenytoin hydroxylation phenotypes in a Jordanian population.

Hakam F. Hadidi, Yacoub M. Irshaid, Raymond L. Woosley, Jeffrey R. Idle, and David A. Flockhart

Clinical Pharmacology & Therapeutics

1995

Monoacetyldapsone inhibition of dapsone N-hydroxylation by human and rat liver microsomes

Yacoub Irshaid, Adedayo Adedoyin, Michael Lutze and Robert A. Branch.

Drug Metabolism and Disposition

Vol. 22, No.1

1994

Debrisoquine 4-hydroxylation (CYP2D6) polymorphism in Jordanians

Hakam F. Hadidi, Suzanne Cholerton, Sophia C. Monkman, Martin Armstrong, Yacoub M. Irshaid, Nayel M. Rawashdeh, Ann K. Daly and Jeffrey R. Idle.

Pharmacogenetics

1994

hydroxylation is a poor probe for debrizoquine oxidation (CYP2D6) polymorphism in Jordanians.

H. F. Al-Hadidi, Y. M. Irshaid and N. M. Rawashdeh.

European Journal of Clinical Pharmacology

1994

Acetylation of dapsone by human whole blood.

Y. M. Irshaid, H. F. Al-Hadidi, M. A. Abuirjeie, N. M. Rawashdeh and N. S. Gharaibeh.

International Journal of Clinical Pharmacology, Therapy and Toxicology

Vol. 31, No.1

1993

Lack of association between glucose-6-phosphate dehydrogenase deficiency and dextromethorphan O-demethylation polymorphism.

Y. M. Irshaid, H. F. Al-Hadidi and N. M. Rawashdeh

European Journal of Clinical Pharmacology

1993

Gastrointestinal dialysis of Digoxin by cholestyramine

Nayel M. Rawashdeh, Hakam F. Al-Hadidi, Yacoub M. Irshaid and Abdel-Kader H. Battah

Pharmacology and Toxicology

1993

Dextromethorphan O-demethylation polymorphism in Jordanians.

Y. M. Irshaid, H. F. Al-Hadidi and N. M. Rawashdeh.

European Journal of Clinical Pharmacology

1993

The acetylator phenotypes of Jordanian diabetics.

Yacoub Irshaid, Hakam Al-Hadidi, Mustafa Abuirjeie, Ali Latif, Omar Sartawi and Nayel Rawashdeh.

European Journal of Clinical Pharmacology

Vol. 43, No. 6

1992

Lack of effect of certain histamine H2-receptor blockers on the glucuronidation of 7-Hydroxy-4-methylcoumarin by human liver microsomes.

Yacoub Irshaid and Mahmood Abu-Khalaf

Pharmacology and Toxicology

1992

Glucuronidation of monohydroxylated short chain bile acids by human liver microsomes and purified human liver UDP-glucuronosyltransferases

Yacoub M. Irshaid, Anna Radominska, Piotr Zimniak, Andrzej Zimniak, Roger Lester and Thomas R. Tephly.

Drug Metabolism and Disposition

Vol. 19, No. 1

1991

Glucuronidation of 7-hydroxy-4-methylcoumarin by microsomes from normal and diseased human livers.

Yacoub Irshaid and Kamal Gharaybeh.

Pharmacology and Toxicology

1991

Simultaneous high performance liquid chromatographic determination of dapsone and monoacetyldapsone in human plasma and urine.

M. A. Abuirjeie, Y. M. Irshaid, H. F. Al-Hadidi and N. M. Rawashdeh.

Journal of Clinical Pharmacy and Therapeutics

1991

N-Acetylation phenotyping using dapsone in a Jordanian population.

Yacoub M. Irshaid, Hakam F. Al-Hadidi, Mustafa A. Abuirjeie and Nayel M. Rawashdeh.

British Journal of Clinical Pharmacology

1991

Characterization and primary sequence of a human hepatic microsomal estriol UDP-glucuronosyltransferase.

Birgit L. Coffman, Thomas R. Tephly, Yacoub M. Irshaid, Mitchell D. Green, Christine Smith, Michael R. Jackson, Richard Wooster and Brian Burchell.

Archives of Biochemistry and Biophysics

Vol. 281, No. 1

1990

Glucuronidation Of 7-hydroxy-4-methylcoumarin by human liver microsomes. Inhibition by certain drugs

Y.M. Irshaid, K.I. Gharaybeh, F.F.Ammari and N.M. Rawashdeh.

European Journal Of Drug Metabolism And Pharmacokinetics

Vol. 15, No. 4

1990

Characterization of antibodies to a rabbit hepatic UDP-glucuronosyltransferase and the identification of an immunologically similar enzyme in human liver

Mitchell D. Green, Birgit L. Coffman, Yacoub M. Irshaid and Thomas R. Tephly.

Archives of Biochemistry and Biophysics

Vol. 262, No. 1

1988

Purification and characterization of mammalian UDP-glucuronosyltransferases

T.R. Tephly, B.L. Coffman, C.N. Falany, M.D. Green, Y. Irshaid, J.F. Puig, S.A. Knapp and J. Baron.

Microsomes and Drug Oxidation

1988

Endogenous substrates for UDP-glucuronosyltransferases

Thomas Tephly, Mitchell Green, Jaime Puig and Yacoub Irshaid.

Xenobiotica

Vol. 18, No. 11

1988

Variability of coumarin 7- and 3-hydroxylation in a Jordanian population is suggestive of a functional polymorphism in cytochrome P450 CYP2A6.

28. Hadidi H, Irshaid. Y, V?agb? CB, Brunsvik A, Cholerton S, Zahlsen K, Idle JR

European Journal of Clinical Pharmacology

Vol. 54, No.5

1988

Isolation and purification of two human liver UDP-glucuronosyltransferases

Yacoub M. Irshaid and Thomas R. Tephly

Molecular Pharmacology

1987

Glucuronidation of 6? -hydroxy bile acids by human liver microsomes.

Anna Radominska-Pyrek, Piotr Zimniak, Yacoub M. Irshaid, Roger Lester, Thomas R. Tephly and Jan St.Pyrek.

Journal Of Clinical Investigation

1987

The formation Of N-glucuronides catalyzed by purified hepatic 17?-hydroxysteroid and 3?-hydroxysteroid UDP-glucuronyltransferases

Mitchell D. Green, Yacoub Irshaid and Thomas R. Tephly

Advances In Experimental Medicine And Biology

197

1986

Published Research // <![CDATA[ _spBodyOnLoadFunctionNames.push("setupPageDescriptionCallout"); // ]]>

Published Research