Theses/Dissertations Supervision

Title	Supervisor/s	Student Name	Specialization	Level	Year	Published or not?	Publisher / Journal	Published or not
The use of computer-aided ligand-based modeling followed by in-vitro assay for the discovery of new epidermal growth factor receptor tyrosin Kinase Inhibitors	Mutasem Taha, Mohammad Khanfar	Laith Al-Shdifat	Drug Design	M.Sc.	2015	Not Published		No
Investigation of novel chemical methodologies for stabilization of chitosan based nanoparticles: Free radicals and metal chelation routes	Mutasem Taha	Safa Daoud	Pharmaceutical Technology	Ph.D.	2015	Not Published		No
Computer-Aided Drug Design and Discovery of new Fibroblast Growth Factor Receptor 1 inhibitors followed by in vitro assay	Mohammad Khanfar Mutasem Taha	Shada Alabed	Drug Design	M.Sc.	2015	Not Published		No
Search for new platelet derived growth factor beta receptor inhibitors for potential anti-angiogenesis therapy via computer-aided molecular modeling followed by bioassay	Mutasem Taha	Ruaa Alaqtash	Drug Design		2015	Not Published		No
Discovery and Chemical Optimization Of Novel Rho Kinase (Rock II) and/or ca2+/calmodulin-dependent protein kinase II (CAMKII) as potential New Anti-Hypertensive Agents.	Mutasem Taha	Rand Shaheen	Drug Design and Organic Synthesis	Ph.D.	2011	Published	Bioorganic and Medicinal Chemistry	Yes
Discovery and Optimization of New Glucokinase Enzyme Activators and/or Glycogen Phosphorylase Enzyme Inhibitors as Potential Anti-Diabetic Agents	Mutasem Taha	Maha A. Habash	Drug Design and Organic Synthesis	Ph.D.	2011	Published	Bioorganic and Medicinal Chemistry	Yes
Discovery and Optimization of new Fructose-1,6-Bisphosphatase (FBP) inhibitors as potential antidiabetic agents	Mutasem Taha	Rabab F. Tayyem	Drug Design	Ph.D.	2011	Not Published		No
Screening towards discovery of new treatments for endometriosis and subsequent mechanistic probe for active hits.	Ahmad Al-Disi Mutasem Taha	Mana Abbas	Biological Studies	Ph.D.	2011	Not Published		No
Optimization of new HSL inhibitors Guided by Pharmacophore and QSAR models	Mutasem Taha Ghassan Abu Sheikha	Jumanah Al-Shawabkeh	Pharmaceutical Sciences	M.Sc.	2011	Not Published		No
Discovery and optimization of new anticancer agents based on daul inhibition of HSP90 and CDK-1 via ligand-based and structure-based modelling followed by in-silico screening, biological evaluation and chemical optimization	Mutasem Taha	Mahmoud A.Al-Sha’er	Drug Design and Organisc Synthesis	Ph.D.	2010	Published	European Journal of Medicinal Chemistry; Journal of Chemical Information and Modelling	Yes
Discovery and optimization of new β-secretase inhibitors as possible treatment for Alzheimer΄s.	Mutasem Taha; Ghassan Abu Sheikha	Afaf Al nadaf	Drug Design and Organic Synthesis	Ph.D.	2010	Published	Bioorganic and Medicinal Chemistry	Yes
Implementation of novel structure-based techniques for the discovery of new N-myristoyl transferase inhibitors as potential antifungal agents	Mutasem Taha; Amal Al-Bakri	Zeina Al-Hadidi	Drug Design	M.Sc.	2010	Not Published		No
Discovery of new cholesteryl ester transfer protein (CETP) inhibitorsvia ligand-based pharmacophore modelling and QSAR analysis and subsequent hit optimization.	Mutasem Taha; Yasser Bustanji	Reema Abu Khalaf	Drug Design and Organic synthesis	Ph.D.	2009	Published	Europen Journal of Medicinal Chemistry	Yes
Discovery and Optimization of new β-D-Glucosidase and β-D-Galactosidase inhibitors via Pharmacophore, QSAR analysis, in-silico Screening and in-vitro Validation.	Mutasem Taha; Mohammad Mubarak	Ahmad Al-Mutanabi	Drug Design and Organic Synthesis	Ph.D.	2009	Published	Journal of Molecular Modelling; Journal of Computational Chemistry	Yes
Preparation of novel matrices based on alginate-chitosan phthalate composites via ionotropic crosslinking with calcium(II) and/or zinc(II) and their evaluation as sustained release formulations using chlorpheniramine maleate as model drug.	Mutasem Taha; Khaled Aiedeh	Arwa Matter	Pharmaceutical Technology	M.Sc.	2009	Not published		No
Design of new NMT inhibitors and Their Biological Evaluation.	Mutasem Taha; Amjad Qandeel	Tareq Al-Hraznah	Drug Designand Microbiology	M.Sc.	2009	Not published		No
Discovery of new estrogen-receptor B (ERB) selective antagonists as potential anti-inflammatory agents	Mutasem O. Taha	Mai Taraira	Drug Design	M.Sc.	2009	Published	Journal of Molecular Graphics and Modelling	Yes
Discovery of dual protein tyrosine phosphatase 1B and dipeptidyl peptidase IV inhibitors via pharmacophore and QSAR analysis followed by in-silico screening and in-vitro and in-vivo experimental validation	Mutasem O. Taha; Mohammad K. Mohammad	Ihab Al-Masri	Drug Design	Ph.D.	2008	Published	ChemMedChem	Yes
Discovery of new Hormone Sensitive Lipase inhibitors via Ligand-based Pharmacophore modeling and QSAR analysis followed by experimental validation.	Mutasem Taha; Yasser Bustanji	Lina Dahabeyah	Drug Design	M.Sc.	2008	Published	Journal of Medicinal Chemistry	Yes
Preparation of novel controlled-release matrices based on alginate-small carboxylic acid composites via ionotropic crosslinking with calcium(II) and/or zinc(II) and their evaluation as sustained release formulations using methylene blue as model drug	Mutasem Taha; Ghassan Abu Sheikha	Reema Ottom	Pharmaceutical Technology	M.Sc.	2008	Not published		No
Modeling the Pharmacophoric Properties of the Skin Pigmentation Enzyme “Tyrosinase” followed by in-silico and in-vitro screening for new hits.	Mutasem O. Taha; Saja Hamed	Rushdi Abu Hamdah	Drug Design	M.Sc.	2007	Not published		No
Docking, CoMFA and Pharmacophor Modeling of the MurF enzyme inhibitors for the discovery of new selective anti-bacterial agents and subsequent experimental validation.	Mutasem Taha; Amal Al-Bakri	Naji Atallah	Drug Design and Microbiology	M.Sc.	2007	Published	Bioorganic and Medicinal Chemistry	Yes
Discovery of new anti-diabetic GSK3B inhibitors using ligand-based pharmacophore mopdelling and experimental validation.	Mutasem O Taha; Yasser Bustanji	Mohammad Al-Ghussein	Drug Design	M.Sc.	2007	Published	Journal of Medicinal Chemistry	Yes
Preparation of novel matrices based on alginate-surfactant composites via ionotropic crosslinking with calcium and/or zinc and their evaluation as sustained release formulations using chlorpeniramine maleate as model drug.	Mutasem O. Taha	Wissam Nasser	Pharmaceutical Technology	M.Sc.	2007	Published	International Journal of Pharmaceutics	Yes
In silico modeling and search for new neurnamindase inhibitors as potential treatments for avian flu.	Mutasem Taha; Fatma Afifi	Areej Abu Hammad	Drug Design	M.Sc.	2006	Published	Journal of Molecular Graphics and Modelling	Yes
Preparation of taste-masking microspheres for the cephalosporin cefataxim axetil.	Mutasem Taha; Khaled Aideh	Abdul Hamid Odeh		M.Sc.	2005	Not published		No
Generation Of An Optimal Pharmacophoric Model For Quorum Sensing Agonists And Antagonists in Pseudomonas aeruginosa Employing Ligand-Based Modeling Techniques And Subsequent Experimental Validation.	Mutasem Taha; Amal Al-Bakri	Waleed Zalloum	Drug Design and Microbiology	M.Sc.	2005	Published	Bioorganic and Medicinal Chemistry Letters	Yes
The Utilization of Catalyst Software for the Discovery of New Potential Anticancer Agents	Mutasem Taha	Ihab Al-Masri	Drug Design	M.Sc.	2003	not published		No
Development of in-silico pharmacophoric models for inhibitors of important key receptors and enzymes involved in the pathogenesis of a group of interrelated circulatory and cardiovascular diseases	Mutasem Taha	Dhia Zaki Dawoud	Miolecular Modelling and Drug Design	M.Sc.	2003	Not Published		No
The utilization of Catalyst software for the discovery of potential anti-viral agents	Mutasem O Taha	Hamadeh Tarazi	Molecular Modeling and Drug Design	M.Sc.	2003	Not published		No

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Theses/Dissertations Supervision